広島大学 脳神経内科学 Hiroshima Univ. Clinical Neuroscience & Therapetics

業績紹介(英文)2002~2011

<2011>

英文原著

Takeda I, Sekine M, Matsushima H, Hosomi N, Nakamura T, Ohtsuki T, Yamawaki T, Matsumoto M.
Two cases of cerebral embolism caused by apical thrombi in midventricular obstructive cardiomyopathy. Internal Medicine. 50(9): 1059-1060, 2011.

 

Ueno H, Kobatake K, Matsumoto M, Morino H, Maruyama H, Kawakami H.
Severe brain atrophy after long-term survival seen in siblings with familial amyotrophic lateral sclerosis and a mutation in the optineurin gene: a case series. J Med Case Rep. 5(1): 573, 2011.

 

Yamazaki Y, Matsubara T, Takahashi T, Kurashige T, Dohi E, Hiji M, Nagano Y, Yamawaki T, Matsumoto M.
Granulovacuolar degenerations appear in relation to hippocampal phosphorylated tau accumulation in various neurodegenerative disorders. PLos One. 6(11): e26996, 2011.

 

Ishihara A, Miyachi T, Nakamura T, Ohtsuki T, Kimura Y, Kihara K, Yamawaki T, Matsumoto M.
Relationship between 3-O-methyldopa and the clinical effects of entacapone in advanced Parkinson's disease. Hiroshima J Med Sci. 60(3): 57-62, 2011.

 

Aoki S, Ohtsuki T, Hosomi N, Sueda Y, Kono T, Yamawaki T, Matsumoto M.
Blood Pressure Variability and Prognosis in Acute Ischemic Stroke with Vascular Compression on the Rostral Ventrolateral Medulla (RVLM). Hypertens Res. 34: 617-22, 2011.

 

Yamazaki Y, Kobatake K, Hara M, Katagiri M, Matsumoto M.
Nutritional support by "conventional" percutaneous endoscopic gastrostomy feeding may not result in weight gain in Parkinson's disease. J Neurol. 258(8): 1561-1563, 2011.

 

Yamazaki Y, Kobatake K.
Successful treatment of nummular headache with Neurotropin(R). J Headache Pain. 12(6): 661-662, 2011.

 

●Fu H, Hosomi N, Pelisch N, Nakano D, Liu G, Ueno M, Miki T, Masugata H, Sueda Y, Itano T, Matsumoto M, NishiyamaA, Kohno M.
Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia. J Hypertens. 29(11): 2210-2219, 2011.

 

●Yuge L, Sasaki A, Kawahara Y, Wu SL, Matsumoto M, Manabe T, Kajiume T, Takeda M, Magaki T, Takahashi T, Kurisu K, Matsumoto M.
Simulated microgravity maintains the undifferentiated state and enhances the neural repair potential of bone marrow stromal cells. STEM CELLS AND DEVELOPMENT. 20(5): 893-900, 2011.

 

●Liu G, Hosomi N, Hitomi H, Pelisch N, Fu H, Masugata H, Murao K, Ueno M, Matsumoto M, Nishiyama A.
Angiotensin II induces human astrocyte senescence through reactive oxygen species production. Hypertens Res. 34(4): 479-483, 2011.

 

Harada T, Ishizaki F, Horie N, Katsuoka H, Nitta Y, Yamada T, Nitta K, Ito M
Alcohol-Induced persistent mild cognitive impairment with successful withdrawal from alcohol dependence –A case report-. Hiroshima Journal of Medical Science. 60(1): 11-13, 2011.

 

●Sugihara K, Maruyama H, Kamada M, Morino H, Kawakami H.
Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population. Neurobiology of Aging. 32(10): 1923.e9-10, 2011.

 

●Kuroda Y, Sako W, Goto S, Sawada T, Uchida D, Izumi Y, Takahashi T, Kagawa N, Matsumoto M, Matsumoto M, Takahashi R, Kaji R, Mitsui T.
Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential. Human Molecular Genetics. 21(5): 991-1003, 2011.

 

●Masugata H, Senda S, Okada H, Murao K, Inukai M, Himoto T, Hosomi N, Murakami K, Noma T, Kohno M, Goda F.

Association between arterial stiffness and pulmonary function in hypertensive patients. Hypertens Res. 35(4): 388-392, 2011.

 

●Noguchi S, Masugata H, Senda S, Ishikawa K, Nakaishi H, Tada A, Inage T, Kajikawa T, Inukai M, Himoto T, Hosomi N, Murakami K, Noma T, Kohno M, Okada H, Goda F, Murao K.

Correlation of arterial stiffness to left ventricular function in patients with reduced ejection fraction. Tohoku J Exp Med. 225(3): 145-151, 2011.

 

●Liu G, Hitomi H, Hosomi N, Lei B, Nakano D, Deguchi K, Mori H, Masaki T, Ma H, Griendling KK, Nishiyama A.

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor. Exp Cell Res. 317(17): 2420-2428, 2011.

 

●Masugata H, Senda S, Inukai M, Murao K, Hosomi N, Iwado Y, Noma T, Kohno M, Himoto T, Goda F.

Differences in left ventricular diastolic dysfunction between eccentric and concentric left ventricular hypertrophy in hypertensive patients with preserved systolic function. J Int Med Res. 39(3): 772-9, 2011.

 

●Masugata H, Senda S, Murao K, Okuyama H, Inukai M, Hosomi N, Iwado Y, Noma T, Kohno M, Himoto T, Goda F.

Aortic root dilatation as a marker of subclinical left ventricular diastolic dysfunction in patients with cardiovascular risk factors. J Int Med Res. 39(1): 64-70, 2011.

 

●Masugata H, Senda S, Inukai M, Himoto T, Murao K, Hosomi N, Iwado Y, Noma T, Kohno M, Goda F.

Seasonal variation in estimated glomerular filtration rate based on serum creatinine levels in hypertensive patients. Tohoku J Exp Med. 224(2): 137-42, 2011.

 

●Masugata H, Senda S, Murao K, Inukai M, Hosomi N, Iwado Y, Noma T, Kohno M, Himoto T, Goda F.

Visit-to-visit variability in blood pressure over a 1-year period is a marker of left ventricular diastolic dysfunction in treated hypertensive patients. Hypertens Res. 34(7): 846-50, 2011.

 

●Masugata H, Senda S, Murao K, Okuyama H, Inukai M, Hosomi N, Iwado Y, Noma T, Kohno M, Goda F.

Association Between Echocardiographic Parameters and Brain Natriuretic Peptide Levels in Treated Hypertensive Patients. Clin Exp Hypertens. 33(3): 187-91, 2011.

 

●Masugata H, Senda S, Inukai M, Murao K, Tada S, Hosomi N, Iwado Y, Noma T, Kohno M, Himoto T, Goda F.

Association between High-Sensitivity C-Reactive Protein and Left Ventricular Diastolic Function Assessed by Echocardiography in Patients with Cardiovascular Risk Factors. Tohoku J Exp Med. 223(4): 263-8, 2011.

 

●Ueno M, Nakagawa T, Nagai Y, Nishi N, Kusaka T, Kanenishi K, Onodera M, Hosomi N, Huang CL, Yokomise H, Tomimoto H, Sakamoto H.
The expression of CD36 in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model. Neuropathol Appl Neurobiol. 37(7): 727-737, 2011.

 

●Masugata H, Senda S, Inukai M, Murao K, Hosomi N, Iwado Y, Noma T, Kohno M, Miyatake N, Himoto T, Goda F.

Association between Bone Mineral Density and Arterial Stiffness in Hypertensive Patients. Tohoku J Exp Med. 223: 85-90, 2011.

 

●Liu G, Hitomi H, Hosomi N, Shibayama Y, Nakano D, Kiyomoto H, Ma H, Yamaji Y, Kohno M, Ichihara A, Itoh H, Nishiyama A.

Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway. J Hypertens. 29(4): 696-705, 2011.

 

●Pelisch N, Hosomi N, Ueno M, Nakano D, Hitomi H, Mogi M, Shimada K, Kobori H, Horiuchi M, Sakamoto H, Matsumoto M, Kohno M, Nishiyama A.

Blockade of AT1 Receptors Protects the Blood-Brain Barrier and Improves Cognition in Dahl Salt-Sensitive Hypertensive Rats. Am J Hypertens. 24(3): 362-8, 2011.

 

Nezu T, Koga M, Nakagawara J, Shiokawa Y, Yamagami H, Furui E, Kimura K, Hasegawa Y, Okada Y, Okuda S, Kario K, Naganuma M, Minematsu K, Maeda K, Toyoda K.
Early ischemic change on CT versus DWI for stroke patients receiving intravenous rt-PA therapy: SAMURAI rt-PA Registry. Stroke. 42(8): 2196-2200, 2011.

 

●Koga M, Kimura K, Shibazaki K, Shiokawa Y, Nakagawara J, Furui E, Yamagami H, Okada Y, Hasegawa Y, Kario K, Okuda S, Naganuma M, Nezu T, Maeda K, Minematsu K, Toyoda K.
CHADS(2) score is associated with 3-month clinical outcomes after intravenous rt-PA therapy in stroke patients with atrial fibrillation: SAMURAI rt-PA Registry. J Neurol Sci. 306(1-2): 49-53, 2011.

 

●Naganuma M, Mori M, Nezu T, Makihara N, Koga M, Okada Y, Mimematsu K, Toyoda K. Intravenous Recombinant Tissue Plasminogen Activator Therapy for Stroke Patients Receiving Maintenance Hemodialysis: The Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement (SAMURAI) rt-PA Registry. Eur Neurol. 66(1): 37-41, 2011.

 

●Tomii Y, Toyoda K, Nakashima T, Nezu T, Koga M, Yokota C, Nagatsuka K, Minematsu K.

Effects of hyperacute blood pressure and heart rate on stroke outcomes after intravenous tissue plasminogen activator. J Hypertens. 29(10): 1980-1987, 2011.

 

●Kikuchi H, Mifune N, Niino M, Ohbu S, Kira J, Kohriyama T, Ota K, Tanaka M, Ochi H, Nakane S, Maezawa M, Kikuchi S.
Impact and characteristics of quality of life in Japanese patients with multiple sclerosis. Qual Life Res. 20(1): 119-31, 2011.

 

●McElroy JP, Isobe N, Gourraud PA, Caillier SJ, Matsushita T, Kohriyama T, Miyamoto K, Nakatsuji Y, Miki T, Hauser SL, Oksenberg JR, Kira J.
SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients. Genes Immun. 12(7): 523-30, 2011.

 

●Kakuda T, Fukuda H, Tanitame K, Takasu M, Date S, Ochi K, Ohshita T, Kohriyama T, Ito K, Matsumoto M, Awai K.

Diffusion tensor imaging of peripheral nerve in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a feasibility study. Neuroradiology. 53(12): 955-60, 2011.

 

 

<2010>

英文原著

●Masugata H, Senda S, Hoshikawa J, Murao K, Hosomi N, Okuyama H, Inukai M, Himoto T, Nakatsuka Y, Imai M, Noma T, Kohno M, Goda F.
Elevated brachial-ankle pulse wave velocity is associated with left ventricular hypertrophy in hypertensive patients after stroke. Tohoku J Exp Med. 220(3): 177-182, 2010.

 

●Ueno M, Onodera M, Naya T, Toyama Y, Hosomi N, Huang CL, Nishiyama Y, Kusaka T, Miki Y, Kohno M, Tomimoto H, Sakamoto H.
Axonal damage in acute cerebral infarction showing ADC reduction. J Neurol. 257(9): 1559-1561, 2010.

 

●Yu X, Murao K, Imachi H, Li J, Nishiuchi T, Hosomi N, Masugata H, Zhang GX, Iwama H, Ishida T. Hyperglycemia Suppresses ABCA1 Expression in Vascular Smooth Muscle Cells. Horm Metab Res. 42(4): 241-246, 2010.

 

●Wang ZY, Miki T, Lee KY, Yokoyama T, Kusaka T, Sumitani K, Warita K, Matsumoto Y, Yakura T, Hosomi N, Ameno K, Bedi KS, Takeuchi Y.
Short-term exposure to ethanol causes a differential response between NGF and BDNF ligand/receptor systems in the mouse cerebellum. Neuroscience. 165(2): 485-491, 2010.

 

●Liu G, Miyata K, Hitomi H, Yao L, Sun GP, Suzaki Y, Hosomi N, Kiyomoto H, Nakano D, Tamaki T, Yoshizumi M, Nishiyama A.
Involvement of mineralocorticoid receptor in high glucose-induced BMK1 activation and mesangial cell proliferation. J Hypertens. 28(3): 536-542, 2010.

 

●Nakamura T, Kuroda Y, Hosomi N, Okabe N, Kawai N, Tamiya T, Xi G, Keep RF, Itano T
Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat. Acta Neurochir Suppl. 106: 307-310, 2010.

 

●Pelisch N, Hosomi N, Liu G, Fu H, Ueno M, Masugata H, Murao K, Hitomi H, Nakano D, Kobori H, Nishiyama A, Kohno M.
Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system. Hypertens Res. 33(2): 161-164, 2010.

 

●Murao K, Imachi H, Ishida T, Hosomi N, Masugata H.
Successful therapy of Cushing's disease caused by an extrapituitary parasellar adenoma. Clin Endocrinol (Oxf)73(1): 133-134, 2010.

 

●Kitaizumi K, Yukiiri K, Masugata H, Takinami H, Iwado Y, Noma T, Hosomi N, Ohmori K, Senda S, Kohno M.
Acute improvement of cardiac efficiency measured by 11C-acetate PET after cardiac resynchronization therapy and clinical outcome. Int J Cardiovasc Imaging. 26(3): 285-292, 2010.

 

●Masugata H, Senda S, Okuyama H, Murao K, Inukai M, Hosomi N, Iwado Y, Noma T, Kohno M, Himoto T, Goda F.
Age-related decrease in inferior vena cava diameter measured with echocardiography. Tohoku J Exp Med. 222(2): 141-147, 2010.

 

●Liu G, Hitomi H, Hosomi N, Lei B, Pelisch N, Nakano D, Kiyomoto H, Ma H, Nishiyama A.
Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells. Hypertens Res. 33(12): 1250-1257, 2010.

 

●Shinohara Y, Katayama Y, Uchiyama S, Yamaguchi T, Handa S, Matsuoka K, Ohashi Y, Tanahashi N, Yamamoto H, Genka C, Kitagawa Y, Kusuoka H, Nishimaru K, Tsushima M, Koretsune Y, Sawada T, Hamada C; CSPS 2 group.
Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial. Lancet Neurol. 9(10): 959-968, 2010.

 

●Masugata H, Senda S, Dobashi H, Himoto T, Murao K, Okuyama H, Inukai M, Hosomi N, Kohno M, Nishiyama Y, Kohno T, Goda F.
Cardio-ankle vascular index for evaluating immunosuppressive therapy in a patient with aortitis syndrome. Tohoku J Exp Med. 222(1): 77-81,2010.

 

●Yamashita S, Kawakita K, Hosomi N, Naya T, Ohkita H, Kuroda Y, Tamiya T.
Reversible magnetic resonance imaging changes associated with hypoglycemia. Case report. Neurol Med Chir (Tokyo). 50(8): 651-654, 2010.

 

●Masugata H, Senda S, Okuyama H, Murao K, Hosomi N, Inukai M, Iwado Y, Noma T, Kohno M, Goda F.
Aortic annular velocity assessed by tissue Doppler echocardiography as a potential parameter of arterial stiffness. Tohoku J Exp Med. 221(2): 169-174, 2010.

 

●Uchiyama S, Shibata Y, Hirabayashi T, Mihara B, Hamashige N, Kitagawa K, Goto S, Origasa H, Shimada K, Kobayashi H, Isozaki M, Ikeda Y; J-TRACE Investigators.
Risk factor profiles of stroke, myocardial infarction, and atrial fibrillation: a Japanese Multicenter Cooperative Registry. J Stroke Cerebrovasc Dis. 19(3): 190-197, 2010.

 

●Yu X, Murao K, Imachi H, Li J, Nishiuchi T, Dobashi H, Hosomi N, Masugata H, Zhang GX, Iwama H, Ishida T.
The transcription factor prolactin regulatory element-binding protein mediates prolactin transcription induced by thyrotropin-releasing hormone in GH3 cells. Endocrine. 38(1): 53-59, 2010.

 

●Masugata H, Senda S, Goda F, Yamagami A, Okuyama H, Kohno T, Hosomi N, Yukiiri K, Noma T, Imai M, Kiyomoto H, Nishiyama A, Kohno M.
Echocardiographic assessment of the cardio-renal connection: is left ventricular hypertrophy or diastolic function more closely correlated with estimated glomerular filtration rate in patients with cardiovascular risk factors? Clin Exp Hypertens. 32(2): 113-120, 2010.

 

●Inoue H, Nozawa T, Hirai T, Goto S, Origasa H, Shimada K, Uchiyama S, Hirabayashi T, Koretsune Y, Ono S, Hasegawa T, Sasagawa Y, Kaneko Y, Ikeda Y; J-TRACE Investigators.

Sex-related differences in the risk factor profile and medications of patients with atrial fibrillation recruited in J-TRACE. Circ J. 74(4): 650-654, 2010.

 

Yamazaki Y, Takahashi T, Hiji M, Kurashige T, Izumi Y, Yamawaki T, Matsumoto M.
Immunopositivity for ESCRT-III subunit CHMP2B in granulovacuolar degeneration of neurons in the Alzheimer's disease hippocampus. Neurosci Lett. 477(2): 86-90, 2010.

 

●Yamamoto K, Seki T, Adachi N, Takahashi T, Tanaka S, Hide I, Saito N, Sakai N
Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy. Genes Cells. 15(5): 425-438, 2010.

 

Miyoshi M, Shinotoh H, Wszolek ZK, Strongosky AJ, Shimada H, Arakawa R, Higuchi M, Ikoma Y, Yasuno F, Fukushi K, Irie T, Ito H, Suhara T.
In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers:A PET and MRI study.Parkinsonism and Related Disorders. 16(6): 404-408, 2010.

 

Yamazaki Y, Ochi K, Nakata Y, Dohi E, Eguchi K, Yamaguchi S, Matsushige T, Ueda T, Amatya VJ, Kohriyama T, Matsumoto M.
Trigeminal neuropathy from perineural spread of an amyloidoma detected by blink reflex and thin-slice magnetic resonance imaging. Muscle&Nerve. 41(6): 875-878, 2010.

 

●Miura H, Hashida K, Sudo H, Awa Y, Takarada-Iemata M, Kokame K, Takahashi T, Matsumoto M, Kitao Y, Hori O.
Deletion of Herp facilitates degradation of cytosolic proteins. Genes Cells. 15(8): 843-53, 2010.
 
●Yuge L, Sasaki A, Kawahara Y, Wu S, Matsumoto M, Manabe T, Kajiume T, Takeda M, Magaki T, Takahashi T, Kurisu K, Matsumoto M.
Simulated microgravity maintains the undifferentiated state and enhances the neural repair potential of bone marrow stromal cells. Stem Cells Dev. 2011 May;20(5): 893-900, 2010.
 
Sueda Y, Naka H, Ohtsuki T, Kono T, Aoki S, Ohshita T, Nomura E, Wakabayashi S, Matsumoto M.
Positional relationship between recurrent intracerebral hemorrhage/Lacunar infarction and previously detected microbleeds. AJNR Am Neuroradiol. 31(8): 1498-1503, 2010.

 

Kondo K, Maruishi M, Ueno H, Sawada K, Hashimoto Y, Ohshita T, Takahashi T, Ohtsuki T, Matsumoto M.
The pathophysiology of prospective memory failure after diffuse axonal -Lesion- symptom analysis using diffusion tensor imaging. BMC Neuroscience. 11(147): 1471-2202, 2010.

 

Ishihara-Kawase K, Ohtasuki T, Sugihara S, Tanaka H, Nakamura T, Kimura A, Matsumoto M.
Cerebral sinus thrombosis heparin-induced thrombocytopenia in patient with paroxysmal nocturnal hemoglobinuria.  Internal Medicine. 49(10): 941-943, 2010.

 

●Lovelock CE, Cordonnier C, Naka H, Salmon R Al-S, Sudlow CLM,Ednburgh Stroke Study Group, Sorimachi T, Werring DJ, Gregoire SM,Imaizumi T., Lee S-H, Briley D., Rothwell PM.
Antithrombotic drug use,cerebral microbleeds, and intraceerebral hemorrhage: A systemic review of published and unpublished studies. Stroke. 41(6): 1222-1228, 2010.

 

Maruyama H, Morino H, Ito H, Izumi Y, Watanabe Y, Kinoshita Y, Kamada M, Nordera H, Suzuki H, Komure O, Matsuura S, Kobatake K, Morimoto N, Abe K, Suzuki N, Aoki M, Kawata A, Hirai T, Kato T, Ogasawara K, Hirano A, Takumi T, Kusaka H, Hagiwara K, Kaji R, Kawakami H.
Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 465(7295): 223-226, 2010.

 

Ueno H, Naka H, Ohshita T, Wakabayashi S, Matsumoto M.
Serial changes in delayed focal hippocampal lesions in patients with transient global amnesia. Hiroshima Journal of Medical Sciences. 59(4): 77-81, 2010.

 

Nezu T, Naganuma M, Shono Y, Toyoda K, Minematsu K.
Central apnoea associated with subcortical haemorrhage in the left temporal lobe. J Neurol Neurosurg Psychiatry. 81(3): 299-301, 2010.

 

Nezu T, Koga M, Kimura K, Shiokawa Y, Nakagawara J, Furui E, Yamagami H, Okada Y, Hasegawa Y, Kario K, Okuda S, Nishiyama K, Naganuma M, Minematsu K, Toyoda K.
Pretreatment ASPECTS on DWI predicts 3-month outcome following rt-PA: SAMURAI rt-PA Registry. Neurology. 75(6): 555-561, 2010.

 

 

<2009>

英文原著

Kawase K, Okazaki S, Toyoda K, Toratani N, Yoshimura S, Kawano H, Nagatsuka K, Matsuo H, Naritomi H, Minematsu K.
Sex difference in the prevalence of deep vein thrombosis in Japanese patients with acute intracerebral hemorrhage. Cerebrovasc Dis. 27: 314-319, 2009.

 

Yamazaki Y, Kobatake K.
The purple urine bag syndrome. BMJ Case Reports. bcr08.2009.2154, 2009.

 

●Yamada M, Mimori Y, Kasagi F, Miyachi T, Ohshita T, Sasaki H.
Incidence and risks of dementia in Japanese women: Radiation Effects Research Foundation Adult Health Study. J Neurol Sci. 283: 57-61, 2009.

 

Ueno H, Maruishi M, Miyatani M, Muranaka H, Kondo K, Ohshita T, Matsumoto M.
Brain activations in errorless and errorful learning in patients with diffuse axonal injury: a functional MRI study. Brain Inj. 23: 291-8, 2009.

 

●Yamada M, Kasagi F, Mimori Y, Miyachi T, Ohshita T, Sasaki H.
Incidence of dementia among atomic-bomb survivors--Radiation Effects Research Foundation Adult Health Study. J Neurol Sci. 281: 11-14, 2009.

 

Shrestha I, Takahashi T, Nomura E, Ohtsuki T, Ohshita T, Ueno H, Kohriyama T, Matsumoto M.
Association between central systolic blood pressure, white matter lesions in cerebral MRI and carotid atherosclerosis. Hypertens Res. 32: 869-874, 2009.

 

Torii T, Nakamori M, Kubo S ,Sugiura T , Yamada A.
Cerebral amyloid angiopathy with a varied hemorrhage pattern on T2*-weighed magnetic resonance imaging. Internal Medicine. 48: 735-736, 2009

 

Shrestha I, Ohtsuki T, Takahashi T, Nomura E, Kohriyama T, Matsumoto M.
Diagonal Ear-Lobe Crease is Correlated with Atherosclerotic Changes in Carotid Arteries. Circulation Jounal. 73(10): 1945-1949, 2009.

 

●Uchiyama S, Goto S, Matsumoto M, Nagai R, Origasa H, Yamazaki T, Shigematsu H, Shimada K, Yamada N, Bhatt DL, Steg PG, Ikeda Y. REduction of Atherothrombosis for Continued Health Registry Investigators.

Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: results from 1-year outcomes in the Japanese REACH Registry. J Neurol Sci. 287: 45-51, 2009.

 

●Masugata H, Senda S, Goda F, Yamagami A, Okuyama H, Kohno T, Yukiiri K, Noma T, Hosomi N, Imai M, Kohno M.
Influences of hypertension and diabetes on normal age-related changes in left ventricular function as assessed by tissue Doppler echocardiography. Clin Exp Hypertens. 31: 400-414, 2009.

 

●Masugata H, Senda S, Okuyama H, Murao K, Inukai M, Hosomi N, Yukiiri K, Nishiyama A, Kohno M, Goda F.

Comparison of central blood pressure and cardio-ankle vascular index for association with cardiac function in treated hypertensive patients. Hypertens Res. 32: 1136-1142, 2009.

 

●Masugata H, Senda S, Himoto T, Murao K, Dobashi H, Kitano Y, Okuyama H, Inukai M, Hosomi N, Kohno M, Nishiyama Y, Kohno T, Goda F.
Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index. Tohoku J Exp Med. 219: 101-105, 2009.

 

●Wu B, Ueno M, Onodera M, Kusaka T, Huang C, Hosomi N, Kanenishi K, Sakamoto H.

RAGE, LDL receptor, and LRP1 expression in the brains of SAMP8. Neurosci Lett. 461: 100-105, 2009.

 

●Masugata H, Senda S, Goda F, Yamagami A, Okuyama H, Kohno T, Hosomi N, Yukiiri K, Noma T, Murao K, Nishiyama A, Kohno M.
Independent determinants of the tei index in hypertensive patients with preserved left ventricular systolic function. Int Heart J. 50: 331-340, 2009.

 

●Nagai Y, Ichihara A, Nakano D, Kimura S, Pelisch N, Fujisawa Y, Hitomi H, Hosomi N, Kiyomoto H, Kohno M, Ito H, Nishiyama A.
Possible contribution of the nonproteolytic activation of prorenin to the development of insulin resistance in fructose-fed rats. Exp Physiol. 94: 1016-1023, 2009.

 

●Masugata H, Senda S, Himoto T, Okuyama H, Inukai M, Murao K, Hosomi N, Yukiiri K, Kohno M, Yamagami A, Kohno T, Goda F.
Early detection of hypertension in a patient treated with sunitinib by measuring cardio-ankle vascular index. Tohoku J Exp Med. 218: 115-119, 2009.

 

●Wu B, Ueno M, Onodera M, Kusaka T, Huang CL, Hosomi N, Kanenishi K, Sakamoto H.
Age-related changes in P-glycoprotein expression in senescence accelerated mouse. Current Aging Science. 2: 187-192, 2009.

 

●Fan YY, Kohno M, Nakano D, Hitomi H, Nagai Y, Fujisawa Y, Lu XM, Fu H, Du J,Ohmori K, Hosomi N, Kiyomoto H, Nishiyama A.

Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats. J Hypertens. 27: 1855-1862, 2009.

 

●Murao K, Imachi H, Yu X, Muraoka T, Hosomi N, Dobashi H, Ishida T.
The transcriptional factor PREB mediates MCP-1 transcription induced by cytokines in human vascular endothelial cells. Atherosclerosis. 207: 45-50, 2009.

 

●Wu B, Ueno M, Kusaka T, Onodera M, Huang C, Hosomi N, Kanenishi K, Sakamoto H.
Abcb1a and Abcb1b expression in senescence-accelerated mouse (SAM). Neurosci Lett. 456: 34-38, 2009.

 

●Masugata H, Senda S, Goda F, Yamagami A, Okuyama H, Kohno T, Hosomi N, Yukiiri K, Noma T, Murao K, Kohno M, Itoh S.
Decline of plasma brain natriuretic peptide during enzyme replacement therapy in a female patient with heterozygous Fabry's disease. Tohoku J Exp Med. 217: 169-174, 2009.

 

●Masugata H, Senda S, Goda F, Yamagami A, Okuyama H, Kohno T, Hosomi N, Yukiiri K, Noma T, Kiyomoto H, Murao K, Nishiyama A, Kohno M.
Tissue Doppler echocardiography for predicting arterial stiffness assessed by cardio-ankle vascular index. Tohoku J Exp Med. 217: 139-146, 2009.

 

●Ueno M, Wu B, Nishiyama A, Huang C, Hosomi N, Kusaka T, Nakagawa T, Onodera M, Kido M, Sakamoto H.

The expression of matrix metalloproteinase-13 (MMP-13) is increased in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model. Hypertens. Res. 32: 332-338, 2009.

 

●Ahmed RA, Murao K, Imachi H, Yoshida K, Dobashi H, Hosomi N, Ishida T.

c-Jun N-terminal kinases inhibitor suppresses the TNF-alpha induced MCP-1 expression in human umbilical vein endothelial cells. Endocrine. 35: 184-188, 2009.

 

Hosomi N, Naya T, Ohkita H, Mukai M, Nakamura T, Ueno M, Dobashi H, Murao K, Masugata H, Miki T, Kohno M, Kobayashi S, Kozio JA.
Predictors of Intracerebral Hemorrhage Severity and Its Outcome in Japanese Stroke Patients. Cerebrovasc Dis. 27: 67-74, 2009.

 

●Ueno M, Nakagawa T, Huang CL, Ueki M, Kusaka T, Hosomi N, Kanenishi K, Onodera M, Wu B, Sakamoto H.
The expression of P-glycoprotein is increased in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model. Neuropath Appl Neuro. 35: 147-155, 2009.

 

 

<2008>

英文原著

Kawase K, Okazaki S, Toyoda K, Toratani N, Yoshimura S, Kawano H, Nagatsuka K, Matsuo H, Naritomi H, Minematsu K.
 Sex difference in the prevalence of deep-vein thrombosis in Japanese patients with acute intracerebral hemorrhage.Cerebrovasc dis. 27: 313-319, 2008.

 

Shrestha I, Ohshita T, Naka H, Morino H, Matsumoto M.
Cytotoxic edema in neuro-Behcet's disease ?. Intern Med. 47: 2073-2076. 2008.

 

●Jin HG, Yamashita H, Nakamura T, Fukuba H, Takahashi T, Hiji M, Kohriyama T, Matsumoto M.
Synphilin-1 transgenic mice exhibit mild motor impairments. Neurosci Lett. 445: 12-17. 2008.

 

Hiji M, Takahashi T, Fukuba H, Yamashita H, Kohriyama T, Matsumoto M.
White matter lesions in the brain with frontotemporal lobar degeneration with motor neuron disease: TDP-43-immunopositive inclusions co-localize with p62, but not ubiquitin. Acta Neuropathol. 116: 183-191. 2008.

 

●Yamada M, Mimori Y, Kasagi F, Miyachi T, Ohshita T, Sudoh S, Ikeda J, Matsui K, Nakamura S, Matsumoto M, Fujiwara S, Sasaki H.
Incidence of dementia, Alzheimer disease, and vascular dementia in a Japanese population: Radiation Effects Research Foundation adult health study. Neuroepidemiology. 30: 152-60. 2008.

 

Fukuba H, Takahashi T, Jin HG, Kohriyama T, Matsumoto M.
Abundance of aspargynyl-hydroxylase FIH is regulated by Siah-1 under normoxic conditions. Neurosci Lett. 15: 209-214. 2008.

 

●Ino T, Usami, Tokumoto K, Kitamura T, Nakamura S.
Transient directional disorientation as a manifestation of cerebral ischemia. Eur Neurol. 60: 43-46. 2008.

 

●Harada T, Ishizaki F, Nitta Y, Nitta K, Shimohara A, Tsukue I, Wu X, Cheng W.
Microchips Will Decrease the Bueden on the Family of Elderly People with Wandering Dementia. International Medical Journal. 15(1): 25-27, 2008.

 

Ueno H, Naka H, Ohshita T, Kondo K, Nomura E, Ohtsuki T, Kohriyama T, Wakabayashi S, Matsumoto M.
Association between cerebral microbleeds on T2*-weighted MR images and recurrent hemorrhagic stroke in patients treated with warfarin following ischemic stroke. AJNR Am J Neuroradiol. 29: 1483-1486, 2008.

 

 

<2007>

英文原著

Yamashita H, Matsumoto M.
Molecular pathogenesis, experimental models and new therapeutic strategies for Parkinson's disease. Regen Med. 2: 447-445. 2007.

 

●Yamazaki T, Goto S, Shigematsu H, Shimada K, Uchiyama S, Nagai R, Yamada N, Matsumoto M, Origasa H, Bhatt DL, Steg PG, Ikeda Y; The REACH Registry Investigators.

Prevalence, awareness and treatment of cardiovascular risk factors in patients at high risk of atherothrombosis in Japan. Circ J. 71: 995-1003, 2007.

 

●Kitagawa K, Hougaku H, Yamagami H, Hashimoto H, Itoh T, Shimizu Y, Takahashi D, Murata S, Seike Y, Kondo K, Hoshi T, Furukado S, Abe Y, Yagita Y, Sakaguchi M, Tagaya M, Etani H, Fukunaga R, Nagai Y, Matsumoto M, Hori M; OSACA2 Study Group.

Carotid intima-media thickness and risk of cardiovascular events in high-risk patients. Results of the Osaka Follow-Up Study for Carotid Atherosclerosis 2 (OSACA2 Study). Cerebrovasc Dis. 24: 35-42, 2007.

 

 

<2006>

英文原著

●Jin C, Katayama S, Hiji M, Watanabe C, Noda K, Nakamura S, Matsumoto M.
Relationship between neuronal loss and tangle formation in neurons and oligodendroglia in progressive supranuclear palsy. Neuropathology 26: 50-56, 2006.

 

Naka H, Nomura E, Takahashi T, Wakabayashi S, Kajikawa H, Kohriyama T, Mimori Y, Matsumoto M.
Plasma total homocysteine levels are associated with advanced leukoaraiosis but not with asymptomatic microbleeds on T2*-weighted MRI in patients with stroke. Eur J Neurol. 13: 261-265, 2006.

 

Naka H, Nomura E, Takahashi T, Wakabayashi S, Mimori Y, Kajikawa H, Kohriyama T, Matsumoto M.
Combinations of the presence or absence of cerebral microbleeds and advanced white matter hyperintensity as predictors of subsequent stroke types. Am J Neuroradiol. 27: 830-835, 2006.

 

●Sato H, Ishikawa K, Kitabatake A, Ogawa S, Maruyama Y, Yokota Y, Fukuyama T, Doi Y, Mochizuki S, Izumi T, Takekoshi N, Yoshida K, Hiramori K, Origasa H, Uchiyama S, Matsumoto M, Yamaguchi T, Hori M; Japan Atrial Fibrillation Stroke Trial Group.
Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke Trial. Stroke. 37: 447-451, 2006.

 

Takahashi T, Yamashita H, Nagano Y, Nakamura T, Kohriyama T, Matsumoto M.
Interactions of Synphilin-1 with phospholipids and lipid membranes.FEBS Lett. 580: 4479-4484, 2006.

 

Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M.
Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. J Neurochem. 98: 45-56, 2006.

 

●Jin HG, Yamashita H, Nagano Y, Fukuba H, Hiji M, Ohtsuki T, Takahashi T, Kohriyama T, Kaibuchi K, Matsumoto M.
Hypoxia-induced upregulation of endothelial small G protein RhoA and Rho-kinase/ROCK2 inhibits eNOS expression. Neurosci Lett. 408: 62-67, 2006.

 

Ohshita T, Kawakami H, Maruyama H, Kohriyama T, Arimura K, Matsumoto M.
Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma. J Neurol Sci. 250: 167-169, 2006.

 

Fukuba H, Yamashita H, Nagano Y, Jin HG, Hiji M, Ohtsuki T, Takahashi T, Kohriyama T, Matsumoto M.
Siah-1 facilitates ubiquitination and degradation of factor inhibiting HIF-1alpha (FIH). Biochem Biophys Res Commun. 353: 324-329, 2006.

 

●Tamura H, Kawakami H, Kanamoto T, Kato T, Yokoyama T, Sasaki K, Izumi Y, Matsumoto M, Mishima H.
High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease. J Neurol Sci. 246: 79-83, 2006.

 

●Alam F, Yasutomi H, Fukuda H, Horiguchi J, Murakami Y, Ohshita T, Inoue K, Ito K.
Diffuse cerebral white matter T2-weighted hyperintensity: a new finding of general paresis. Acta Radiol. 47: 609-611, 2006.

 

●Toda K, Muneshige H, Asou T, Harada T, Okazaki M, Tachiki N, Horie N, Cheng W, Nakamura S.
Basal blood flow in complex regional pain syndrome does not necessarily indicate vasoconstrictor nerve activity. Clin. J Pain. 22: 109-110, 2006.

 

●Hayashi Y, Hashizume T, Wakida K, Satoh M, Uchida Y, Watabe K, Matsuyama Z, Kimura A, Inuzuka T, Hozumi I.
Association between metallothionein genes polymorphisms and sporadic amyotrophic lateral sclerosis in a Japanese population. Amyotroph Lateral Scler. 7: 22-26, 2006.

 

●Oki K, Noda K, Kondo K, Koide J.
Rhabdomyolysis associated with hyponatremia and adrenal insufficiency. Eur J Neurol. 13: e8-9, 2006.

 

●Shibazaki K, Murakami T, Kushida R, Kurokawa K, Terada K, Sunada Y.
Acute disseminated encephalomyelitis associated with oral polio vaccine. Intern Med. 45: 1143-1146, 2006.

 

●Nodera H, Bostock H, Izumi Y, Nakamura K, Urushihara R, Sakamoto T, Murase N, Shimazu H, Kusunoki S, Kaji R.
Activity-dependent conduction block in multifocal motor neuropathy: magnetic fatigue test. Neurology. 67: 280-287, 2006.

 

●Zabetian CP, Morino H, Ujike H, Yamamoto M, Oda M, Maruyama H, Izumi Y, Kaji R, Griffith A, Leis BC, Roberts JW, Yearout D, Samii A, Kawakami H.
Identification and haplotype analysis of LRRK2 G2019S in Japanese patients with Parkinson disease. Neurology. 67: 697-699, 2006.

 

●Seki T, Irie N, Nakamura K, Sakaue H, Ogawa W, Kasuga M, Yamamoto H, Ohmori S, Saito N, Sakai N.
Fused protein of deltaPKC activation loop and PDK1-interacting fragment (deltaAL-PIF) functions as a pseudosubstrate and an inhibitory molecule for PDK1 when expressed in cells. Genes Cells. 11: 1051-1070, 2006.

 

●Mochizuki H, Seki T, Adachi N, Saito N, Mishima HK, Sakai N.
R659S mutation of gammaPKC is susceptible to cell death: implication of this mutation/polymorphism in the pathogenesis of retinitis pigmentosa. Neurochem Int. 49: 669-675, 2006.

 

●Suzuki T, Hide I, Matsubara A, Hama C, Harada K, Miyano K, Andra M, Matsubayashi H, Sakai N, Kohsaka S, Inoue K, Nakata Y.
Microglial alpha7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role. J Neurosci Res. 83: 1461-1470, 2006.

 

●Matsui H, Nishinaka K, Oda M, Komatsu K, Kubori T, Udaka F.
Adult onset hemiparkinsonism with brain hemihypoplasia. Neurol India. 54: 450-451, 2006.

 

●Matsui H, Nishinaka K, Oda M, Komatsu K, Kubori T, Udaka F.
Minor depression and brain perfusion images in Parkinson's disease. Mov Disord. 21: 1169-1174, 2006.

 

●Hiramoto K, Kawakami H, Inoue K, Seki T, Maruyama H, Morino H, Matsumoto M, Kurisu K, Sakai N.
Identification of a new family of spinocerebellar ataxia type 14 in the Japanese spinocerebellar ataxia population by the screening of PRKCG exon 4. Mov Disord. 21: 1355-1360, 2006.

 

●Matsui H, Nishinaka K, Oda M, Hara N, Komatsu K, Kubori T, Udaka F.
Hypoperfusion of the visual pathway in parkinsonian patients with visual hallucinations. Mov Disord. 21: 2140-2144, 2006.

 

●Matsui H, Nishinaka K, Oda M, Hara N, Komatsu K, Kubori T, Udaka F.
Hypoperfusion of the auditory and prefrontal cortices in Parkinsonian patients with verbal hallucinations. Mov Disord. 21: 2165-2169, 2006.

 

●Matsui H, Nishinaka K, Oda M, Hara N, Komatsu K, Kubori T, Udaka F.
Excessive daytime sleepiness in Parkinson disease: a SPECT study. Sleep. 29: 917-20, 2006.

 

●Matsui H, Udaka F, Oda M, Kubori T, Nishinaka K, Kameyama M.
Encephalopathy and severe neuropathy due to probable systemic vasculitis as an initial manifestation of mixed connective tissue disease. Neurol India. 54: 83-85, 2006.

 

●Matsui H, Nishinaka K, Oda M, Hara N, Komatsu K, Kubori T, Udaka F.
Wisconsin Card Sorting Test and brain perfusion imaging in Parkinson's disease. Parkinsonism Relat Disord. 12: 273-278, 2006.

 

●Matsui H, Nishinaka K, Oda M, Komatsu K, Kubori T, Udaka F.
Does cardiac metaiodobenzylguanidine (MIBG) uptake in Parkinson's disease correlate with major autonomic symptoms? Parkinsonism Relat Disord. 12: 284-288, 2006.

 

●Matsui H, Nishinaka K, Oda M, Niikawa H, Komatsu K, Kubori T, Udaka F.
Disruptions of the fornix fiber in Parkinsonian patients with excessive daytime sleepiness. Parkinsonism Relat Disord. 12: 319-322, 2006.

 

●Matsui H, Udaka F, Kubori T, Oda M, Nishinaka K, Oka N.
HTLV-I-associated peripheral neuropathy with smoldering-type adult T-cell leukemia. Neurologist. 12: 109-113, 2006.

 

●Matsui H, Udaka F, Oda M, Tamura A, Kubori T, Nishinaka K, Kameyama M.
Parkinson's disease following panic disorder. J Neuropsychiatry Clin Neurosci. 18: 130, 2006.

 

●Matsui H, Udaka F, Tamura A, Oda M, Kubori T, Nishinaka K, Kameyama M.
Impaired visual acuity as a risk factor for visual hallucinations in Parkinson's disease. J Geriatr Psychiatry Neurol. 19: 36-40, 2006.

 

●Matsui H, Udaka F, Miyoshi T, Hara N, Tamura A, Oda M, Kubori T, Nishinaka K, Kameyama M.
Frontal assessment battery and brain perfusion image in Parkinson's disease. J Geriatr Psychiatry Neurol. 19: 41-45, 2006.

 

●Lee JH, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M, Arriaga A, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawarai T, George-Hyslop PS, Mayeux R.
Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease. Arch Neurol. 63: 1591-1598, 2006.

 

●Murakami T, Paitel E, Kawarabayashi T, Ikeda M, Chishti MA, Janus C, Matsubara E, Sasaki A, Kawarai T, Phinney AL, Harigaya Y, Horne P, Egashira N, Mishima K, Hanna A, Yang J, Iwasaki K, Takahashi M, Fujiwara M, Ishiguro K, Bergeron C, Carlson GA, Abe K, Westaway D, George-Hyslop PS, Shoji M.
Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation. Am J Pathol. 169: 1365-1375, 2006.

 

●Momeni P, Rogaeva E, Van Deerlin V, Yuan W, Grafman J, Tierney M, Huey E, Bell J, Morris CM, Kalaria RN, van Rensburg SJ, Niehaus D, Potocnik F, Kawarai T, Salehi-Rad S, Sato C, George-Hyslop PS, Hardy J.
Genetic variability in CHMP2B and frontotemporal dementia. Neurodegener Dis. 3: 129-133, 2006.

 

●Wislet-Gendebien S, D'Souza C, Kawarai T, George-Hyslop PS, Westaway D, Fraser P, Tandon A.
Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes. J Biol Chem. 281: 32148-32155, 2006.

 

●Rogaeva E, Zadikoff C, Ponesse J, Schmitt-Ulms G, Kawarai T, Sato C, Salehi-Rad S, St George-Hyslop P, Lang AE.
Childhood onset in familial prion disease with a novel mutation in the PRNP gene. Arch Neurol. 63: 1016-1021, 2006.

 

●Kaneko S, Kawarai T, Yip E, Salehi-Rad S, Sato C, Orlacchio A, Bernardi G, Liang Y, Hasegawa H, Rogaeva E, George-Hyslop PS.
Novel SPG6 mutation p.A100T in a Japanese family with autosomal dominant form of hereditary spastic paraplegia. Mov Disord. 21: 1531-1533, 2006.

 

●Alves da Costa C, Sunyach C, Pardossi-Piquard R, Sevalle J, Vincent B, Boyer N, Kawarai T, Girardot N, George-Hyslop PS, Checler F.
Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease. J Neurosci. 26: 6377-6385, 2006.

 

●Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, George-Hyslop PS, Fraser P.
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 440: 1208-1212, 2006.

 

●Dunys J, Kawarai T, Wilk S, George-Hyslop PS, Alves da Costa C, Checler F.
Catabolism of endogenous and overexpressed APH1a and PEN2: evidence for artifactual involvement of the proteasome in the degradation of overexpressed proteins. Biochem J. 394 :501-509, 2006.

 

●Munhoz RP, Kawarai T, Teive HA, Raskin S, Sato C, Liang Y, George-Hyslop PS, Rogaeva E.
Clinical and genetic study of a Brazilian family with spastic paraplegia (SPG6 locus). Mov Disord. 21: 279-281, 2006.

 

●Shibata N, Kawarai T, Lee JH, Lee HS, Shibata E, Sato C, Liang Y, Duara R, Mayeux RP, George-Hyslop PS, Rogaeva E.
Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease. Neurosci Lett. 391: 142-146, 2006.

 

●Bernardi L, Maletta RG, Tomaino C, Smirne N, Di Natale M, Perri M, Longo T, Colao R, Curcio SA, Puccio G, Mirabelli M, Kawarai T, Rogaeva E, George Hyslop PS, Passarino G, De Benedictis G, Bruni AC.

The effects of APOE and tau gene variability on risk of frontotemporal dementia. Neurobiol Aging. 27: 702-709, 2006.

 

●Kitagawa K, Yagita Y, Sasaki T, Matsushita K, Matsumoto M, Hori M.
Temporal profile of cells with proteolipid protein mRNA signals in the? hippocampus after transient global ischemia. J Cereb Blood Flow Metab. 18: 1-6, 2006.

英文総説

Matsumoto M.
 Cilostazol in secondary prevention of stroke: impact of the Cilostazol Stroke Prevention Study. Atheroscler Suppl. 6: 33-40, 2006.

 

●Rogaeva E, Kawarai T, George-Hyslop PS.
 Genetic complexity of Alzheimer's disease: successes and challenges. J Alzheimers Dis. 9 (3 Suppl): 381-387, 2006.

 

 

<2005>

英文原著

● Matsumoto M.
Cilostazol in secondary prevention of stroke: impact of the Cilostazol Stroke Prevention Study. Atheroscler Suppl. Dec. 15;6(4): 33-40, 2005.

 

Inoue K, Shirai T, Nakanishi K, Hashizume A, Harada T, Mimori Y, Matsumoto M.
Difference in somatosensory evoked fields elicited by mechanical and electrical stimulations: Elucidation of the human homunculus by a noninvasive method. Hum Brain Mapp. 24: 274-283, 2005.

 

●Oku N, Kitagawa K, Imaizumi M, Takasawa M, Piao R, Kimura Y, Kajimoto K, Matsumoto M, Hori M, Hatazawa J.
Hemodynamic Influences of Losartan on the Brain in Hypertensive Patients. Hypertens Res. 28: 43-49, 2005.

 

●Horie N, Inoue K, Shirai T, Hashizume A, Nakanishi K, Harada T, Kawakami H, Kohriyama T, Mimori Y, Matsumoto M.
Activation of human SII cortex during exploratory finger movement and hand clenching tasks. Neuroreport. 16: 145-148, 2005.

 

Nomura E, Matsumoto M.
 Cerebral Infarction and Patent Foramen Ovale (PFO) in the Elderly: Is PFO the Culprit or Not? Intern Med. 44: 401-402, 2005.

 

●Seki T, Adachi N, Ono Y, Mochizuki H, Hiramoto K, Amano T, Matsubayashi H, Matsumoto M, Kawakami H, Saito N, Sakai N.
Mutant Protein Kinase CγFound in Spinocerebellar Ataxia Type 14 Is Susceptible to Aggregation and Causes Cell Death. J Biol Chem. 280: 29096-29106, 2005.

 

Shingo A. S, Kito S.
Estradiol induces PKA activation through the putative membrane receptor in the living hippocampal neuron. J Neural Transm. 112: 1469-1473, 2005.

 

Shingo A. S, Kito S.
Effects of nicotine on neurogenesis and plasticity of hippocampal neurons. J Neural Transm. 112: 1475-1478, 2005.

 

●Yamagami H, Kitagawa K, Ohtsuki T, Matsumoto M, Hori M.
Embolic Cerebral Infarction Caused by Intraluminal Thrombus in the Carotid Siphon Successfully Treated With Combination of Anticoagulant and Antiplatelet Drugs. Circ J. 69: 1147-1149, 2005.

 

Matsumoto M.
Cilostazol in secondary prevention of stroke: impact of the Cilostazol Stroke Prevention Study. Atheroscler Suppl. 6: 33-40, 2005.

 

●Kitagawa K, Hori M, Matsumoto M.
Future Aspects of Gene Therapy in Acute Ischemic Stroke. Intern Med. 44 :371-374, 2005.

 

Nomura E, Kohriyama T, Matsumoto M, Kobayasi S, Japan Standard Stroke Registry Study(JSSRS)Group.
Clinical Characteristics of First-Ever Atherothrombotic Infarction or Lacunar Infarction with Hyperlipidemia (J-STARS-C): An Analysis of Data from the Stroke Data Bank of Japan. Intern Med. 44: 1252-1257, 2005.

 

●Hamaguchi T, Kitamoto T, Sato T, Mizusawa H, Nakamura Y, Noguchi M, Fukukawa Y, Ishida C, Kuji I, Mitani K, Murayama S, Kohriyama T, Katayama S, Yamashita M, Yamamoto T, Udaka F, Kawakami A, Ihara Y, Nishinaka T, Kuroda S, Suzuki N, Shiga Y, Arai H, Maruyama M, Yamada M.
Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease. Neurology. 64: 643-648, 2005.

 

●Nishimura M, Kuno S, Kaji R, Kawakami H.
Influence of a tumor necrosis factor gene polymorphism in Japanese patients with multiple system atrophy. Neurosci Lett. 374: 218-221, 2005.

 

●Nishimura M, Kuno S, Kaji R, Yasuno K, Kawakami H.
Glutathione-S-Transferase-1 and Interleukin-1β Gene Polymorphisms in Japanese Patients With Parkinson’s Disease. Mov Disord. 20: 901-902, 2005

 

●Nishimura M, Kuno S, Kaji R, Kawakami H.
Brain-Derived Neurotrophic Factor Gene Polymorphisms in Japanese Patients With Sporadic Alzheimer’s Disease, Parkinson’s Disease, and Multiple System Atrophy. Mov Disord. 20: 1031-1059, 2005.

 

●Asai H, Udaka F, Hirano M, Minami T, Oda M, Kubori T, Nishinaka K, Kameyama M, Ueno S.
Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson’s disease. Parkinsonism Relat Disord. 11: 499-502, 2005.

 

●Matsui H, Udaka F, Tamura A, Oda M, Kubori T, Nishinaka K, Kameyama M.
Multiple Sclerosis Following Splenectomy as a Treatment for Idiopathic Thrombocytopenic Purpura. Intern Med. 44: 747-749, 2005.

 

●Matsui H, Udaka F, Miyoshi T, Hara N, Tamaura A, Oda M, Kubori T, Nishinaka K, Kameyama M.
Three-Dimensional Stereotactic Surface Projection Study of Freezing of Gait and Brain Perfusion Image in Parkinson’s Disease. Mov Disord. 20: 1272-1277, 2005.

 

●Matsui H, Udaka F, Kubori T, Oda M, Nishinaka K, Kameama M.
Persistent Primitive Hypoglossal Artery with Atrial Septal Defect. Intern Med. 44: 507-508, 2005.

 

●Matsui H, Udaka F, Miyoshi T, Hara N, Tamura A, Oda M, Kubori T, Nishinaka K, Kameyama M.
Three-dimensional stereotactic surface projection study of orthostatic hypotension and brain perfusion image in Parkinson’s disease. Acta Neurol Scand. 112: 36-41, 2005.

 

●Matsui H, Udaka F, Miyoshi T, Hara N, Tamura A, Oda M, Kubori T, Nishinaka K, Kmayama M.
Brain perfusion differences between Parkinson’s disease and multiple system atrophy with predominant parkinsonian features. Parkinsonism Relat Disord. 11: 227-232, 2005.

 

●Matsui H, Udaka F, Miyoshi T, Hara N, Tamura A, Oda M, Kubori T, Nishinaka K, Kameyama M.
N-isopropyl-p-123I Iodoamphetamine Single Photon Emission Computed Tomography Study of Parkinson’s Disease with Dementia. Intern Med. 44: 1046-1050, 2005.

 

●Sakaguchi M, Kitagawa K, Oku N, Imaizumi M, Yamagami H, Ohtsuki T, Matsushima K, Hougaku H, Matsumoto M, Hatazawa J, Hori M.
Critical Analysis of Hemodynamic Insufficiency by Head-up Tilt in Patients With Carotid Occlusive Disease. Circ J. 69: 971-975, 2005.

 

●Oku N, Kitagawa K, Imaizumi M, Takasawa M, Piao R, Kimura Y, Kajimoto K, Matsumoto M, Hori M, Hatazawa J.
Hemodynamic Influences of Losartan on the Brain in Hypertensive Patients. Hypertens Res. 28: 43-49, 2005.

 

●Matsui H, Udaka F, Tamura A, Oda M, Kubori T, Nshinaka K, Kameyama M.
The relation between visual hallucinations and visual evoked potential in Parkinson disease. Clin Neuropharmaco. l28: 79-82, 2005.

 

●Matsui H, Udaka F, Oda M, Kubori T, Nishinaka K, Kameyama M.
Metaiodobenzylguanidine (MIBG) scintigraphy at various parts of the body in Parkinson’s disease and multiple system atrophy. Auton Neurosci. 119: 56-60, 2005.

 

●Matsui H, Udaka F, Oda M, Tamura A, Kubori T, Nishinaka K, Kameyama M.
Metaiodobenzylguanidine (MIBG) uptake in Parkinson’s disease also decreases at thyroid. Ann Nucl Med. 19: 225-229, 2005.

 

●Mitsuoka T, Watanabe C, Torii T, Naka T, Katayama S, Mizusaki N, Matsumoto M.
Visual event-related potentials evoked by three-dimensional images in healthy controls. Int Congr Ser. 1278: 153-155, 2005.

 

●Fukuda H, Horiguchi J, Ono C, Ohshita T, Takaba J, Ito K.
Diffusion tensor imaging of cerebral white matter in patients with myotonic dystrophy. Acta Radiol. 46: 104-109, 2005.

 

●Yano Y, Kario K, Fukunaga T, Ohshita T, Himeji D, Yano M, Nakagawa S, Sakata Y, Shimada K.
A case of reversible posterior leukoencephalopathy syndrome caused by transient hypercoagulable state induced by infection. Hypertens Res. 28: 619-623, 2005.

 

●Nagai M, Yamada H, Kitamoto M, Ikeda J, Mori Y, Monzen Y, Fukuhara T.
Facial nerve palsy due to temporal bone metastasis from hepatocellular carcinoma. J Gastroenterol Hepatol. 20: 1131-1139, 2005.

 

●Konishi Y, Shirabe T, Katayama S, Funakawa I, Terao A.
Autopsy case of pure akinesia showing pallidonigro-luysian atrophy. Neuropathology. 25, 220-227, 2005.

 

●Nitta Y, Araki N, Nitta K, Harada T, Ishizaki F, Ando J.
Effects of high linear energy transfer radiation on the cochlea of C3H/He in mouse during postnatal development course. J Radiat Res. 46: 75-81, 2005.

 

●Nitta Y, Araki N, Nitta K, Harada T, Ishizaki F, Cheng W, Ando J.
Effect of monoenergetic neutron irradiation on the postnatal development of the cochlea in C3H/HeN mice. J Vet Med Sci. 67: 577-582, 2005.

 

●Cheng W, Harada T, Ishizaki F, Yin H, Wang Q, Ma L, Nitta Y, Nitta K, Ohtani H.
Changes in plasma IL-13 in patients with acute cerebral infarction. International Med J. 12: 33-35, 2005.

 

Harada T, Ishizaki F, Tachiki N, Matsumoto T, Horie N, Inoue K, Nakamura S, Nitta Y, Nitta K, Inoue Y, Oikawa K, Masumi M, Tuyama K, Ohtani M, Ohtani M, Ohtani H.
Circadian rhythm of cardiovascular autonomic function in Parkinson’s disease and multiple system atrophy. International Med J. 12: 37-39, 2005.

 

●Wu X, Harada T, Ishizaki F, Horie N, Nitta Y, Nitta K.
Study on the effect of Xinnaotongluo liquid on hemorheology in patients with coronary heart disease. International Med J. 12: 129-131, 2005.

 

Harada T, Ishizaki F, Nitta Y, Nitta K, Yamada T.
Effect of pramipexole treatment for depression in Japanese patients with Parkinson’s disease. J Psychosomatic Res. 58: S84-S85, 2005.

 

●Wang Z, Harada T, Wu X, Li Y, Ishizaki F, Horie N, Nitta Y, Nitta K, Tsukue I.
Relationship between characteristics of soybean isoflavone treatment and climacteric syndrome. International Med J. 12: 195-197, 2005.

 

Harada T, Ishizaki F, Yamamura Y, Nakamura S, Date Y, Nakazato M, Nitta Y, Nitta K, Tsukue I.
Relationship between characteristics of genetic study and polyneuropathy in aged patients. International Med J. 12: 291-293, 2005.

 

●Mochizuki H, Amano T, Seki T, Matsubayashi H, Mitsuhata C, Morita K, Kitayama S, Dohi T, Mishima K. M, Sakai N.
Role of C-terminal region in the functional regulation of rat serotonin transporter (SERT). Neurochem. Int. 46: 93-105, 2005.

 

●Seki T, Matsubayashi H, Amano T, Shirai Y, Saito N, Sakai N.
Phosphorylation of PKC activation loop plays an important role in receptor-mediated translocation of PKC. Genes to Cells. 10: 225-239, 2005.

 

●Fukunaga-Takenaka R, Shirai Y, Yagi K, Adachi N, Sakai N, Merino E, Merida I, Saito N.
Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase α by d-α-tocopherol. Genes to Cells. 10: 311-319, 2005.

 

●Abdel-Raheem I. T, Hide I, Yanase Y, Shigemtoto-Nogami Y, Sakai N, Shirai Y, Saito N, Hamada F.H, El-Mahdy N. A, Elsisy A. E-D. E, Sokar S. S, Nakata Y.
Protein kinase C α mediates TNF release process in RBL-2H3 mast cells. Br. J. Pharmacol. 145: 415-423, 2005.

 

●Kodama N, Murata Y, Asakawa A, Inui A, Hayashi M, Sakai N, Nanba H.
Maitake D-fraction enhences antitumor effects and reduced immunosupression by mitomycin-C in tumor-bearing mice. Nutrition. 21: 624-629, 2005.

 

●Hirano K, Seki T, Sakai N, Hashimoto H, Uchida S, Yamada S.
Effects of continuous administration of paroxetine on ligand binding site and expression of serotonin transporter protein in mouse brain. Brain Res. 1053: 154-161, 2005.

 

●Paisan-Ruiz C, Lang AE, Kawarai T, Sato C, Salehi-Rad S, Fisman GK, Al-Khairallah T, St George-Hyslop P, Singleton A, Rogaeva E.
LRRK2 gene in Parkinson disease: mutation analysis and case control association study. Neurology. 65: 696-700, 2005.

 

●Orlacchio A, Kawarai T, Gaudiello F, St George-Hyslop PH, Floris R, Bernardi G.
New locus for hereditary spastic paraplegia maps to chromosome 1p31.1-1p21.1. Ann Neurol. 58: 423-429, 2005.

 

●Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, Hasegawa H, Salehi-Rad S, Wang L, Rogaeva E, Fraser P, Robinson B, St George-Hyslop P, Tandon A.
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J Biol Chem. 280: 34025-34032, 2005.

 

●Moonis M, Swearer JM, Dayaw MP, St George-Hyslop P, Rogaeva E, Kawarai T, Pollen DA
Familial Alzheimer disease: decreases in CSF Abeta42 levels precede cognitive decline. Neurology. 65: 323-325, 2005.

 

●Pardossi-Piquard R, Petit A, Kawarai T, Sunyach C, Alves da Costa C, Vincent B, Ring S, D'Adamio L, Shen J, Muller U, St George Hyslop P, Checler F
Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron. 46: 541-554, 2005.

 

●Orlacchio A, Kawarai T, Gaudiello F, Totaro A, Schillaci O, Stefani A, Floris R, St George-Hyslop PH, Sorbi S, Bernardi G.
Clinical and genetic study of a large SPG4 Italian family. Mov Disord. 20: 1055-1059, 2005.

 

●Ikeda M, Shoji M, Kawarai T, Kawarabayashi T, Matsubara E, Murakami T, Sasaki A, Tomidokoro Y, Ikarashi Y, Kuribara H, Ishiguro K, Hasegawa M, Yen SH, Chishti MA, Harigaya Y, Abe K, Okamoto K, St George-Hyslop P, Westaway D
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice. Am J Pathol. 166: 521-531, 2005.

 

●Sato C, Morgan A, Lang AE, Salehi-Rad S, Kawarai T, Meng Y, Ray PN, Farrer LA, St George-Hyslop P, Rogaeva E
Analysis of the glucocerebrosidase gene in Parkinson's disease. Mov Disord. 20: 367-370, 2005.

英文総説

Nomura E, Matsumoto M.
Cerebral infarction and patent foramen ovale (PFO) in the elderly: Is PFO the culprit or not? Intern Med. 44: 401-402, 2005.

 

 

<2004>

英文原著

Oda M, Maruyama H, Izumi Y, Morino H, Torii T, Nakamura S, Kawakami H.
Dinucleotide repeat polymorphism in interferon-gamma gene is not associated with sporadic Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet. 124: 48-49, 2004.

 

Oda M, Maruyama H, Komure O, Morino H, Terasawa H, Izumi Y, Imamura T, Yasuda M, Ichikawa K, Ogawa M, Matsumoto M, Kawakami H.
Possible reduced penetrance of expansion of 44 to 47 CAG/CAA repeats in the TATA-binding protein gene in spinocerebellar ataxia type 17. Arch Neurol. 61: 209-212, 2004.

 

Terasawa H, Oda M, Morino H, Miyachi T, Izumi Y, Maruyama H, Matsumoto M, Kawakami H.
A novel haplotype of spinocerebellar ataxia type 6 contributes to the highest prevalence in western Japan. Neurosci Lett. 358: 107-110, 2004.

 

●Yamagami H, Kitagawa K, Nagai Y, Hougaku H, Sakaguchi M, Kuwabara K, Kondo K, Masuyama T, Matsumoto M, Hori M.
Higher levels of interleukin-6 are associated with lower echogenicity of carotid artery plaques. Stroke. 35: 677-681, 2004.

 

Matsuoka N, Kohriyama T, Ochi K, Nishitani M, Sueda Y, Mimori Y, Nakamura S, Matsumoto M.
Detection of cervical nerve root hypertrophy by ultrasonography in chronic inflammatory demyelinating polyradiculoneuropathy. J Neurol Sci. 219: 15-21, 2004.

 

●Kitagawa K, Matsumoto M, Hori M.
Cerebral ischemia in 5-lipoxygenase knockout mice. Brain Res. 1004: 198-202, 2004.

 

●Ayukawa R, Fujimoto H, Ayabe M, Shoji H, Matsui R, Iwata Y, Fukuda H, Ochi K, Noda K, Ono Y, Sakai K, Takehisa Y, Yasui K.
An unexpected outbreak of Japanese encephalitis in the Chugoku District of Japan, 2002. Jpn J Infect Dis. 57: 63-66, 2004.

 

Nomura E, Kohriyama T, Kozuka K, Kajikawa H, Nakamura S, Matsumoto M.
Significance of serum soluble thrombomodulin level in acute cerebral infarction. Eur J Neurol. 11: 329-334, 2004.

 

Naka H, Nomura E, Wakabayashi S, Kajikawa H, Kohriyama T, Mimori Y, Nakamura S, Matsumoto M.
Frequency of asymptomatic microbleeds on T2*-weighted MR images of patients with recurrent stroke: association with combination of stroke subtypes and leukoaraiosis. AJNR Am J Neuroradiol. 25: 714-719, 2004.

 

Shirai T, Inoue K, Hashizume A, Nakanishi K, Harada T, Mimori Y, Matsumoto M.
Human reactions to physical stimulus and the removal of such stimulus as recorded by magnetoencephalography. Neurosci Lett. 362: 10-13, 2004.

 

Honjo K, Ohshita T, Kawakami H, Naka H, Imon Y, Maruyama H, Mimori Y, Matsumoto M.
Quantitative assessment of cerebral blood flow in genetically confirmed spinocerebellar ataxia type 6. Arch Neurol. 61: 933-937, 2004.

 

Inoue K, Hashimoto I, Shirai T, Kawakami H, Miyachi T, Mimori Y, Matsumoto M.
Disinhibition of the somatosensory cortex in cervical dystonia-decreased amplitudes of high-frequency oscillations. Clin Neurophysiol. 115: 1624-1630, 2004.

 

●Sasaki T, Kitagawa K, Yamagata K, Takemiya T, Tanaka S, Omura-Matsuoka E, Sugiura S, Matsumoto M, Hori M.
Amelioration of hippocampal neuronal damage after transient forebrain ischemia in cyclooxygenase-2-deficient mice. J Cereb Blood Flow Metab. 24: 107-113, 2004.

 

●Seike Y, Hashikawa K, Oku N, Moriwaki H, Yamamoto H, Fukuchi K, Watanabe Y, Matsumoto M, Hori M, Nishimura T.
Evaluation of the use of a standard input function for compartment analysis of [123I]iomazenil data: factors influencing the quantitative results. Ann Nucl Med. 18: 563-572, 2004.

 

Kumagai-Eto R, Kaseda Y, Tobimatsu S, Uozumi T, Tsuji S, Nakamura S.
Subclinical cranial nerve involvement in hereditary motor and sensory neuropathy: a combined conduction study with electrical and magnetic stimulation. Clin Neurophysiol. 115: 1689-1696, 2004.

 

●Yamada M, Kasagi F, Sasaki H, Mimori Y, Suzuki G.
Effects of dementia on mortality in the radiation effects research foundation adult health study. Gerontology. 50: 110-112, 2004.

 

Honjo K, Okada H, Sumii K, Kobatake T, Fujioka S, Kumagai I, Takeda S, Teraoka A.
Endoscopy is one of the valuable diagnostic methods for primary aorto-enteric fistula: report of a case. Digestive Endoscopy. 16: 353-354, 2004.

 

●Matsui H, Udaka F, Kubori T, Oda M, Nishinaka K, Kameyama M.
POEMS syndrome demonstrating VEGF decrease by ticlopidine. Intern Med. 43: 1082-1083, 2004.

 

●Toda T, Muneshige H, Asou T, Harada T, Okazaki M, Tachiki N, Horie N, Nakamura S.
Simultaneous examination of skin blood flow and sweating in complex regional pain syndrome: report of one case. The Pain Clinic. 16: 213-216, 2004.

 

Harada T, Yamamura Y, Ishizaki F, Togo M.
Difference of clinical characteristics and brain-stem function between Parkinson’s disease and early-onset parkinsonism. Jpn J Physiol. 54 (Suppl): S24, 2004.

 

●Nitta Y, Yoshida K, Nakagata N, Harada T, Ishizaki F, Nitta K, Torii M.
Effects of a hemizygous deletion of mouse chromosome 2 on the hematopoietic and intestinal tumorigenesis. J Toxicol Pathol. 17: 105-112, 2004.

 

●Wu X, Li Y, Harada T, Ishizaki F, Nitta Y, Nitta K, Ohtani H.
Study on relation between hypertension and the function of nitric oxide as the messenger. Int Med J. 11: 115-117, 2004.

 

●Yin H, Cheng W, Harada T, Ishizaki F, Nitta Y, Nitta K, Ohtani H.
An analysis of apolipoprotein E polymorphism in aged patients with vascular dementia. Int Med J. 11 (4): 291-293, 2004.

 

程 為平、馬 莉、王 喜武、原田俊英.
Treatment of vascular dementia by Naozhitong capsule: A clinical observation of 18 cases. 新中医.36: 16-18, 2004.

英文総説

Nakamura S.
 A guideline for the treatment of dementia in Japan. Intern Med. 43:18-29, 2004.

 

 

<2003>

英文原著

Ochi K, Kohriyama T, Higaki M, Ikeda J, Harada A, Nakamura S.
Changes in serum macrophage-related factors in patients with chronic inflammatory demyelinating polyneuropathy caused by intravenous immunoglobulin therapy. J Neurol Sci. 208: 43-50, 2003.

 

Nomura E, Kohriyama T, Kajikawa H, Nakamura S, Matsumoto M.
Significance of Serum Soluble Thrombomodulin Level in Acute Cerebral Infarction. Neurology. 60 (suppl 1): A372-373, 2003.

 

●Narita M, Kitagawa K, Nagai Y, Hougaku H, Hashimoto H, Sakaguchi M, Yang X, Takeshita T, Morimoto K,Matsumoto M, Hori M.
Effects of aldehyde dehydrogenase genotypes on carotid atherosclerosis. Ultrasound Med Biol. 29: 1415-1419, 2003.

 

●Yamada M, Kasagi F, Sasaki H, Masunari N, Mimori Y, Suzuki G.
Association between dementia and midlife risk factors: the Radiation Effects Research Foundation Adult Health Study. J Am Geriatr Soc. 51: 410-414, 2003.

 

Izumi Y, Maruyama H, Oda M, Morino H, Okada T, Ito H, Sasaki I, Tanaka H, Komure O, Udaka F, Nakamura S, Kawakami H.
SCA8 repeat expansion: large CTA/CTG repeat alleles are more common in ataxic patients, including those with SCA6. Am J Hum Genet. 72: 704-709, 2003.

 

●Nishimura M, Kuno S, Mizuta I, Ohta M, Maruyama H, Kaji R, Kawakami H.
Influence of monocyte chemoattractant protein 1 (MCP-1) gene polymorphism on age-at-onset of sporadic Parkinson's disease. Mov Disord. 18: 953-964, 2003.

 

Inoue K, Shirai T, Hashizume A, Harada T, Kaseda Y, Mimori Y, Nakamura S, Matsumoto M.
Somatosensory-evoked fields in Alzheimer's disease. International Congress Series. 1252: 411-415, 2003.

 

Mitsuoka T, Watanabe C, Kitamura J, Ishigame K, Nakamura S.
Movement-related cortical potentials in myotonic dystrophy. Clin Neurophysiol. 114: 99-106, 2003.

 

Takahashi T, Yamashita H, Nagano Y, Nakamura T, Ohmori H, Avraham H, Avraham S, Yasuda M,
 Matsumoto M
Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation. J Biol Chem. 278: 42225-42233, 2003.

 

Nagano Y, Yamashita H, Takahashi T, Kishida S, Nakamura T, Iseki E, Hattori N, Mizuno Y, Kikuchi A,  Matsumoto M.
Siah-1 facilitates ubiquitination and degradation of synphilin-1. J Biol Chem. 278: 51504-51514, 2003.

 

 

<2002>

英文原著

●Shinoda-Tagawa T, Yamasaki Y, Yoshida S, Kajimoto Y, Tsujino T, Hakui N, Matsumoto M, Hori M.
A phosphodiesterase inhibitor, cilostazol, prevents the onset of silent brain infarction in Japanese subjects with TypeⅡdiabetes. Diabetologia. 45: 188-194, 2002.

 

Tanaka S, Kitagawa K, Ohtsuki T, Yagita Y, Takasawa K, Hori M, Matsumoto M.
Synergistic induction of HSP40 and HSC70 in the mouse hippocampal neurons after cerebral ischemia and ischemic tolerance in gerbil hippocampus. J Neurosci Res. 67: 37-47, 2002.

 

●Kitagawa K, Matsumoto M, Sasaki T, Hashimoto H, Kuwabara K, Ohtsuki T, Hori M.
Involvement of ICAM-1 in the progression of atherosclerosis in APOE-knockout mice. Atherosclerosis. 160: 305-310, 2002.

 

●Kitagawa K, Takasawa K, Kuwabara K, Sasaki T, Tanaka S, Mabuchi T, Sugiura S, Omura-Matsuoka E, Matsumoto M, Hori M.
Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats. Neurosci Lett. 333: 187-190, 2002.

 

●Takasawa K, Kitagawa K, Yagita Y, Sasaki T, Tanaka S, Matsushita K, Ohtsuki T, Miyata T, Okano H, Hori M, Matsumoto M.
Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats. J Cereb Blood Flow Metab. 22: 299-307, 2002.

 

Mitsuoka T, Kaseda Y, Yamashita H, Kohriyama T, Kawakami H, Nakamura S, Yamamura Y.
Effects of nicotine chewing gum on UPDRS score and P300 in early-onset Parkinsonism. Hiroshima J Med Sci. 51: 33-39, 2002.

 

●Kitagawa K, Matsumoto M, Kuwabara K, Takasawa K, Tanaka S, Sasaki T, Matsushita K, Ohtsuki T, Yanagihara T, Hori M.
Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action. J Neurosci Res. 68: 226-232, 2002.

 

Nakamura T, Yamashita H, Nagano Y, Takahashi T, Avraham S, Avraham H, Matsumoto M, Nakamura S.
Activation of Pyk2/RAFTK induces tyrosine phosphorylation of alpha-synuclein via Src-family kinases. FEBS Lett. 521: 190-194, 2002.

 

●Takasawa M, Murase K, Oku N, Yoshikawa T, Osaki Y, Imaizumi M, Matsuzawa H, Fujino K, Hashikawa K, Kitagawa K, Hori M, Matsumoto M.
Assessment of acetazolamide reactivity in cerebral blood flow using spectral analysis and technetium-99m hexamethylpropylene amine oxime. J Cereb Blood Flow Metab. 22: 1004-1009, 2002.

 

●Takasawa M, Watanabe M, Yamamoto S, Hoshi T, Sasaki T, Hashikawa K, Matsumoto M, Kinoshita N.
Prognostic value of subacute crossed cerebellar diaschisis: Single-photon emission CT study in patients with middle cerebral artery territory infarct. AJNR Am J Neuroradiol. 23: 189-193, 2002.

 

●Imaizumi M, Kitagawa K, Hashikawa K, Oku N, Teratani T, Takasawa M, Yoshikawa T, Rishu P, Ohtsuki T, Hori M, Matsumoto M, Nishimura T.
Detection of misery perfusion with split-dose 123I-iodoamphetamine single-photon emission computed tomography in patients with carotid occlusive diseases. Stroke. 33: 2217-2223, 2002.

 

●Takasawa M, Kitagawa K, Ohtsuki T, Oku N, Hashikawa K, Sakoda S, Hori M, Matsumoto M.
Prominent matched hypoperfusion in an intact cerebellum after a solitary middle cerebellar peduncle infarct. Am J Neuroradiol. 23: 1356-1358, 2002.

 

Yagita Y, Kitagawa K, Sasaki T, Miyata T, Okano H, Hori M, Matsumoto M.
Differential expression of musashi1 and nestin in the adult rat hippocampus after ischemia. J Neurosci Res. 69: 750-756, 2002.

 

●Nagai Y, Matsumoto M, E Jeffrey Metter.
The carotid artery as a noninvasive window for cardiovascular risk in apparently healthy individuals. Ultrasound Med Biol. 28: 1231-1238, 2002.

 

●Nagai Y, Kitagawa K, Yamagami H, Kondo K, Hougaku H, Hori M, Matsumoto M.
Carotid artery intima-media thickness and plaque score for the risk assessment of stroke subtypes. Ultrasound Med Biol. 28: 1239-1243, 2002.

 

●Iiji O, Nagai Y, Itoh T, Hougaku H, Kitagawa K, Hori M, Matsumoto M.
Smoking habit as a putative risk factor for carotid plaque ulcers. J Stroke Cerebrovasc Dis. 11: 320-323, 2002.

 

●Takasawa M, Murase K, Oku N, Kawamata M, Imaizumi M, Yoshikawa T, Osaki Y, Asit K. Paul, Kitagawa K, Matsumoto M, Hori M.
Automati determination of brain perfusion index for measurement of cerebral blood flow using spectral analysis and 99mTc-HMPAO. Eur J Nucl Med. 29: 1443-1446, 2002.

 

●Sasaki T, Watanabe M, Nagai Y, Hoshi T, Takasawa M, Nukata M, Taguchi A, Kitagawa K, Kinoshita N, Matsumoto M.
Association of plasma homocysteine concentration with atherosclerotic carotid plaques and lacunar infarction. Stroke. 33: 1493-1496, 2002.

 

Matsumoto M.
Anti-hypertensive treatment and stroke recurrence: inpact of progress. Brain Hemorrhage. 35-42, 2002.

 

Nomura E, Kohriyama T, Kajikawa H, Nakamura S, Matsumoto M.
Serum level of soluble thrombomodulin in acute ischemic stroke. European Jounal of Neurology. 9 (supplement 2): 113-114, 2002.

 

Harada T, Ishizaki F, Murakami I, Tachiki N, Horie N, Matsumoto T, Nitta K, Nakamura S.
Age-related changes in P300 event-related potentials in Japanese normal volunteers. Int Med J. 9: 41-43, 2002.

 

Harada T, Ishizaki F, Murakami I, Yamaguchi S, Nitta K, Nakamura S.
Relationship between P300 event-related potentials and autonomic nervous dysfuction. Int Med J. 9: 125-130, 2002.

 

Harada T, Ishizaki F, Yamaoka K, Furukawa Y, Fujiwara C, Nitta K, Kambe M, Nakamura S.
Genetic study of type 2 diabetes mellitus using polymerase chain reaction (PCR) genotyping. Int Med J. 9: 169-171, 2002.

 

Harada T, Ishizaki F, Tachiki N, Nitta K, Nakamura S.
Evaluation of gastric emptying in Parkinson's disease. Int Med J. 9: 209-213, 2002.

 

Harada T, Ishizaki F, Yamamura Y, Inoue K, Tachiki N, Imamura R, Horie N, Matsumoto T, Hide M, Nitta K, Nakamura S.
Short-term natural remission of cholinergic urticaria associated with epileptic seizure and abnormalities on electroencephalogram. Int Med J. 9: 225-227, 2002.

 

Harada T, Ishizaki F, Cheng W.P, Horie N, Tachiki N, Okazaki M, Nitta K, Nakamura S.
Analysis of skin autonomic nervous function in patients with neurodegenerative diseases. Int Med J. 9: 275-278, 2002.

 

Harada T, Cheng W.P, Ishizaki F, Inoue K, Horie N, Nakamura S.
The study on correlation of Parkinson's disease and function of autonomic nerves in circulatory system. Hei Long Jiang Medical Journal. 26: 575-576, 2002.

 

Maruyama H, Izumi Y, Morino H, Oda M, Toji H, Nakamura S, Kawakami H.
Difference in disease-free survival curve and regional distribution according to subtype of spinocerebellar ataxia: A study of 1,286 Japanese patients. Am J Med Genet. 114: 578-583, 2002.

 

Oda M, Morino H, Maruyama H, Terasawa H, Izumi Y, Torii T, Sasaki K, Nakamura S, Kawakami H.
Dinucleotide repeat polymorphisms in the neprilysin gene are not associated with sporadic Alzheimer’s disease. Neurosci Lett. 320: 105-107, 2002.

 

●Nishimura M, Kawakami H, Komure O, Maruyama H, Morino H, Izumi Y, Nakamura S, Kaji R, Kuno S.
Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy. Movement Disorders. 17: 808-811, 2002.

 

●Nishimura M, Matsuoka M, Maeda M, Mizuta I, Mita S, Uchino M, Matsui M, Kuroda Y, Kawakami H, Kaji R, Adachi A, Uchiyama T.
Association between interleukin-6 gene polymorphism and human T-Cell leukemia virus type I associated myelopathy. Human Immunol. 63: 696-700, 2002.

 

Takahashi T, Yamashita H, Nakamura T, Nagano Y, Nakamura S.
Tyrosine 125 of ?synuclein plays a critical role for dimerization following nitrative stress. Brain Res. 938: 73-80, 2002.

 

Kozuka K, Kohriyama T, Nomura E, Ikeda J, Kajikawa H, Nakamura S.
Endothelial markers and adhesion molecules in acute ischemic stroke--sequential change and differences in stroke subtype. Atherosclerosis. 161: 161-168, 2002.

 

Naka H, Imon Y, Ohshita T, Honjo K, Kitamura T, Miyachi T, Katayama S, Mimori Y, Nakamura S.
Magnetization transfer measurements of brain structures in patients with multiple system atrophy. NeuroImage. 17: 1572-1578, 2002.

 

Shimizu ME, Ishizaki F, Nakamura S.
Results of a home exercise program for patients with osteoporosis resulting from neurological disorders. Hiroshima J Med Sci. 51: 15-22, 2002.

 

Naka H, Ohshita T, Murata Y, Imon Y, Mimori Y, Nakamura S.
 Characteristic MRI findings in multiple system atrophy: comparison of the three subtypes. Neuroradiology. 44: 204-209, 2002.

 

Naka H, Imon Y, Ohshita T, Honjo K, Kitamura T, Mimori Y, Nakamura S.
Magnetization transfer measurements of cerebral white matter in patients with myotonic dystrophy. J Neurol Sci. 193: 111-116, 2002.

 

Inoue K, Yamashita T, Harada T, Nakamura S.
Role of human SII cortices in sensorimotor integration. Clin Neurophysiol. 113: 1573-1578, 2002.

 

Kawakami H, Inoue K, Sakakihara I, Nakamura S.
Novel mutation in X-linked Charcot-Marie-Tooth disease associated with CNS impairment. Neurology. 59: 923-926, 2002.

 

Inoue K, Mimori Y, Nakamura S.
N10 potential as an antidromic motor evoked potential in a median nerve short-latency somatosensory evoked potential study. J Clin Neurophysiol. 19: 37-42, 2002.

 

Inoue K, Harada T, Kaseda Y, Mimori Y, Hashizume A, Hashimoto I, Matsumoto M.
Effects of movement on somatosensory N20m fields and high-frequency oscillations. NeuroReport. 13: 1861-1864, 2002.

 

●Ogura H, Yasuda M, Nakamura S, Yamashita H, Mikoshiba K, Ohmori H.
Neurotoxic damage of granule cells in the dentate gyrus and the cerebellum and cognitive deficit following neonatal administration of phenytion in mice. J Neuropathol Exp Neurol. 61: 956-967, 2002.

 

●Shoji M, Matsubara E, Murakami T, Manabe Y, Abe K, Kanai M, Ikeda M, Tomidokoro Y, Shizuka M, Watanabe M, Amari M, Ishiguro K, Kawarbayashi T, Harigaya Y, Okamoto K, Nishimura T, Nakamura Y, Takeda M, Urakami K, Adachi Y, Nakashima K, Arai H, Sasaki H, Kanemaru K, Yamanouchi H, Yoshida Y, Ichise K, Tanaka K, Hamamoto M, Yamamoto H, Matsubayashi T, Yoshida H, Toji H, Nakamura S, Hirai S.
Cerebrospinal fluid tau in dementia disorders: a large scale multicenter study by a Japanesr study group. Neurobiol Aging. 23: 363-370, 2002.

 

Sakata K, Shigemasa K, Uebaba Y, Nagai N, Ohama K.
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma. Acta Cytologia. 46: 697-703, 2002.